Pathways and Terms for Health, Aging, Senescence and Rejuvenation
Georg Fuellen
University of Rostock, Germany
Do we really know what we are talking about? Given the variety in the usage of terms such as "biological age" or "biomarker of aging", and a lack of clean definitions, there may be doubts. Thus, in the first part, a brief overview of work on a generic framework of definitions of important terms will be presented, including an operational definition of health.
How can we systematically investigate the molecular underpinnings of health and senescence? Systematic work could deliver a
bird's-eye view of the molecular biology that may be most relevant for health, for undoing its deterioration and for precision prevention. Thus, in the second part, I will be presenting "pathway maps" of health and of cellular senescence, and showcase how these may be utilized.
University of Rostock, Germany
Do we really know what we are talking about? Given the variety in the usage of terms such as "biological age" or "biomarker of aging", and a lack of clean definitions, there may be doubts. Thus, in the first part, a brief overview of work on a generic framework of definitions of important terms will be presented, including an operational definition of health.
How can we systematically investigate the molecular underpinnings of health and senescence? Systematic work could deliver a
bird's-eye view of the molecular biology that may be most relevant for health, for undoing its deterioration and for precision prevention. Thus, in the second part, I will be presenting "pathway maps" of health and of cellular senescence, and showcase how these may be utilized.
